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5alpha-hydroxysteroid dehydratase

From Wikipedia, the free encyclopedia
5α-hydroxysteroid dehydratase
Identifiers
EC no.4.2.1.62
CAS no.9075-27-8
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO
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PMCarticles
PubMedarticles
NCBIproteins

The enzyme 5α-hydroxysteroid dehydratase (EC 4.2.1.62) catalyzes the chemical reaction

5α-ergosta-7,22-diene-3β,5-diol ergosterol + H2O

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase (ergosterol-forming). This enzyme is also called 5α-ergosta-7,22-diene-3β,5-diol 5,6-hydro-lyase.

References

[edit]
  • Topham RW, Gaylor JL (1970). "Isolation and purification of a 5 alpha-hydroxysterol dehydrase of yeast". J. Biol. Chem. 245 (9): 2319–27. PMID 5442273.